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Validations of SCT Methylation as a Hallmark Biomarker for Lung Cancers

BACKGROUND: The human secretin (SCT) gene encodes secretin, a hormone with limited tissue distribution. Analysis of The Cancer Genome Atlas (TCGA) 450K methylation array data indicated that the SCT promoter region is differentially hypermethylated in lung cancer. Our purpose was to validate SCT meth...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Zhang, Yu-An, Ma, Xiaotu, Sathe, Adwait, Fujimoto, Junya, Wistuba, Ignacio, Lam, Stephen, Yatabe, Yasushi, Wang, Yi-Wei, Stastny, Victor, Gao, Boning, Larsen, Jill E, Girard, Luc, Liu, Xiaoyun, Song, Kai, Behrens, Carmen, Kalhor, Neda, Xie, Yang, Zhang, Michael Q, Minna, John D, Gazdar, Adi F
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809190/
https://ncbi.nlm.nih.gov/pubmed/26725182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2015.11.004
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