Pre-Clinical Studies of Epigenetic Therapies Targeting Histone Modifiers in Lung Cancer

Por Huffman, Kenneth, Martinez, Elisabeth D.
Publicado em 2013

A Subset of Nuclear Receptors are Uniquely Expressed in Uveal Melanoma Cells

Por Huffman, Kenneth Edward, Carstens, Ryan, Martinez, Elisabeth D.
Publicado no Front Endocrinol (Lausanne) (2015)

Quantitative Secretomic Analysis Identifies Extracellular Protein Factors that Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer

Por Hu, Rongkuan, Huffman, Kenneth E., Chu, Michael, Zhang, Yajie, Minna, John D., Yu, Yonghao
Publicado no J Proteome Res (2016)

Normal human chromosomes have long G-rich telomeric overhangs at one end

Por Wright, Woodring E., Tesmer, Valerie M., Huffman, Kenneth E., Levene, Stephen D., Shay, Jerry W.
Publicado em 1997

A Systematic Analysis Reveals Heterogeneous Changes in the Endocytic Activities of Cancer Cells

Por Elkin, Sarah R., Bendris, Nawal, Reis, Carlos R., Zhou, Yunyun, Xie, Yang, Huffman, Kenneth E., Minna, John D., Schmid, Sandra L.
Publicado no Cancer Res (2015)

Targeting Thyroid Hormone Receptor Beta in Triple Negative Breast Cancer

Por Gu, Guowei, Gelsomino, Luca, Covington, Kyle R., Beyer, Amanda R., Wang, John, Rechoum, Yassine, Huffman, Kenneth, Carstens, Ryan, Ando, Sebastiano, Fuqua, Suzanne A.W.
Publicado no Breast Cancer Res Treat (2015)

ESR1 Mutations Affect Anti-proliferative Responses to Tamoxifen through Enhanced Cross-Talk with IGF Signaling

Por Gelsomino, Luca, Gu, Guowei, Rechoum, Yassine, Beyer, Amanda R, Pejerrey, Sasha M, Tsimelzon, Anna, Wang, Tao, Huffman, Kenneth, Ludlow, Andrew, Ando’, Sebastiano, Fuqua, Suzanne AW
Publicado no Breast Cancer Res Treat (2016)

Quantitative proteomic analysis of optimal cutting temperature (OCT) embedded core-needle biopsy of lung cancer

Por Zhao, Xiaozheng, Huffman, Kenneth E., Fujimoto, Junya, Canales, Jamie Rodriguez, Girard, Luc, Nie, Guangjun, Heymach, John V., Wistuba, Igacio I., Minna, John D., Yu, Yonghao
Publicado no J Am Soc Mass Spectrom (2017)

Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells

Por Wang, Xu-Dong, Hu, Rongkuan, Ding, Qing, Savage, Trisha K., Huffman, Kenneth E., Williams, Noelle, Cobb, Melanie H., Minna, John D., Johnson, Jane E., Yu, Yonghao
Publicado no Nat Commun (2019)

Inhibition of Cancer Cell Proliferation by PPARγ is Mediated by a Metabolic Switch that Increases Reactive Oxygen Species Levels

Por Srivastava, Nishi, Kollipara, Rahul K., Singh, Dinesh K., Sudderth, Jessica, Hu, Zeping, Nguyen, Hien, Wang, Shan, Humphries, Caroline G., Carstens, Ryan, Huffman, Kenneth E., DeBerardinis, Ralph J., Kittler, Ralf
Publicado em 2014

Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells

Por Yan, Yunfeng, Liu, Li, Xiong, Hu, Miller, Jason B., Zhou, Kejin, Kos, Petra, Huffman, Kenneth E., Elkassih, Sussana, Norman, John W., Carstens, Ryan, Kim, James, Minna, John D., Siegwart, Daniel J.
Publicado no Proc Natl Acad Sci U S A (2016)

Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5

Por Tian, Hui, Lu, Jui-Yun, Shao, Chunli, Huffman, Kenneth E., Carstens, Ryan M., Larsen, Jill E., Girard, Luc, Liu, Hui, Rodriguez-Canales, Jaime, Frenkel, Eugene P., Wistuba, Ignacio I., Minna, John D., Hofmann, Sandra L.
Publicado no Mol Cancer Res (2015)

LCE: an open web portal to explore gene expression and clinical associations in lung cancer

Por Cai, Ling, Lin, ShinYi, Girard, Luc, Zhou, Yunyun, Yang, Lin, Ci, Bo, Zhou, Qinbo, Luo, Danni, Yao, Bo, Tang, Hao, Allen, Jeffrey, Huffman, Kenneth, Gazdar, Adi, Heymach, John, Wistuba, Ignacio, Xiao, Guanghua, Minna, John, Xie, Yang
Publicado no Oncogene (2018)

Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer

Por Cai, Ling, Lin, ShinYi, Girard, Luc, Zhou, Yunyun, Yang, Lin, Ci, Bo, Zhou, Qinbo, Luo, Danni, Yao, Bo, Tang, Hao, Allen, Jeffrey, Huffman, Kenneth, Gazdar, Adi, Heymach, John, Wistuba, Ignacio, Xiao, Guanghua, Minna, John, Xie, Yang
Publicado no Oncogene (2019)

NRF2 regulates serine biosynthesis in non-small cell lung cancer

Por DeNicola, Gina M., Chen, Pei-Hsuan, Mullarky, Edouard, Sudderth, Jessica A., Hu, Zeping, Wu, David, Tang, Hao, Xie, Yang, Asara, John M., Huffman, Kenneth E., Wistuba, Ignacio I., Minna, John D., DeBerardinis, Ralph J., Cantley, Lewis C.
Publicado no Nat Genet (2015)

SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures

Por Tlemsani, Camille, Pongor, Lorinc, Elloumi, Fathi, Girard, Luc, Huffman, Kenneth E., Roper, Nitin, Varma, Sudhir, Luna, Augustin, Rajapakse, Vinodh N., Sebastian, Robin, Kohn, Kurt W., Krushkal, Julia, Aladjem, Mirit I., Teicher, Beverly A., Meltzer, Paul S., Reinhold, William C., Minna, John D., Thomas, Anish, Pommier, Yves
Publicado no Cell Rep (2020)

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis

Por Padanad, Mahesh S., Konstantinidou, Georgia, Venkateswaran, Niranjan, Melegari, Margherita, Rindhe, Smita, Mitsche, Matthew, Yang, Chendong, Batten, Kimberly, Huffman, Kenneth E., Liu, Jingwen, Tang, Ximing, Rodriguez-Canales, Jaime, Kalhor, Neda, Shay, Jerry W., Minna, John D., McDonald, Jeffrey, Wistuba, Ignacio I., DeBerardinis, Ralph J., Scaglioni, Pier Paolo
Publicado no Cell Rep (2016)

Inosine monophosphate dehydrogenase dependence in a subset of small cell lung cancers

Por Huang, Fang, Ni, Min, Chalishazar, Milind D., Huffman, Kenneth E., Kim, Jiyeon, Cai, Ling, Shi, Xiaolei, Cai, Feng, Zacharias, Lauren G., Ireland, Abbie S., Li, Kailong, Gu, Wen, Kaushik, Akash K., Liu, Xin, Gazdar, Adi F., Oliver, Trudy G., Minna, John D., Hu, Zeping, DeBerardinis, Ralph J.
Publicado no Cell Metab (2018)

Cancer-specific production of N-acetylaspartate via NAT8L overexpression in non-small cell lung cancer and its potential as a circulating biomarker

Por Lou, Tzu-Fang, Sethuraman, Deepa, Dospoy, Patrick, Srivastva, Pallevi, Kim, Hyun Seok, Kim, Joongsoo, Ma, Xiaotu, Chen, Pei-Hsuan, Huffman, Kenneth E., Frink, Robin E., Larsen, Jill E., Lewis, Cheryl, Um, Sang-Won, Kim, Duk-Hwan, Ahn, Jung-Mo, DeBerardinis, Ralph J., White, Michael A., Minna, John D., Yoo, Hyuntae
Publicado no Cancer Prev Res (Phila) (2015)

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

Por Kim, Jiyeon, Hu, Zeping, Cai, Ling, Li, Kailong, Choi, Eunhee, Faubert, Brandon, Bezwada, Divya, Rodriguez-Canales, Jaime, Villalobos, Pamela, Lin, Yu-Fen, Ni, Min, Huffman, Kenneth E., Girard, Luc, Byers, Lauren A., Unsal-Kacmaz, Keziban, Peña, Christopher G., Heymach, John V., Wauters, Els, Vansteenkiste, Johan, Castrillon, Diego H., Chen, Benjamin P.C., Wistuba, Ignacio, Lambrechts, Diether, Xu, Jian, Minna, John D., DeBerardinis, Ralph J.
Publicado no Nature (2017)