Kynurenine: an oncometabolite in colon cancer

由 Venkateswaran, Niranjan, Conacci-Sorrell, Maralice
發表在 Cell Stress (2020)

MYC leads the way

由 Venkateswaran, Niranjan, Conacci-Sorrell, Maralice
發表在 Small GTPases (2017)

Nullifying the CDKN2A/B Locus Promotes Mutant K-ras Lung Tumorigenesis

由 Schuster, Katja, Venkateswaran, Niranjan, Rabellino, Andrea, Girard, Luc, Peña-Llopis, Samuel, Scaglioni, Pier Paolo
出版 2014

Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis

由 Ramadori, Giorgio, Konstantinidou, Georgia, Venkateswaran, Niranjan, Biscotti, Tommasina, Morlock, Lorraine, Galié, Mirco, Williams, Noelle S., Luchetti, Michele, Santinelli, Alfredo, Scaglioni, Pier Paolo, Coppari, Roberto
發表在 Cell Metab (2015)

Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells

由 Lafita-Navarro, M. Carmen, Venkateswaran, Niranjan, Kilgore, Jessica A., Kanji, Suman, Han, Jungsoo, Barnes, Spencer, Williams, Noelle S., Buszczak, Michael, Burma, Sandeep, Conacci-Sorrell, Maralice
發表在 PLoS Genet (2020)

Focal Adhesion Kinase regulates the DNA damage response and its inhibition radiosensitizes mutant KRAS lung cancer

由 Tang, Ke-Jing, Constanzo, Jerfiz, Venkateswaran, Niranjan, Melegari, Margherita, Ilcheva, Mariya, Morales, Julio C., Skoulidis, Ferdinandos, Heymach, John V., Boothman, David A., Scaglioni, Pier Paolo
發表在 Clin Cancer Res (2016)

The aryl hydrocarbon receptor regulates nucleolar activity and protein synthesis in MYC-expressing cells

由 Lafita-Navarro, M. Carmen, Kim, Min, Borenstein-Auerbach, Nofit, Venkateswaran, Niranjan, Hao, Yi-Heng, Ray, Roshni, Brabletz, Thomas, Scaglioni, Pier Paolo, Shay, Jerry W., Conacci-Sorrell, Maralice
發表在 Genes Dev (2018)

MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

由 Venkateswaran, Niranjan, Lafita-Navarro, M. Carmen, Hao, Yi-Heng, Kilgore, Jessica A., Perez-Castro, Lizbeth, Braverman, Jonathan, Borenstein-Auerbach, Nofit, Kim, Min, Lesner, Nicholas P., Mishra, Prashant, Brabletz, Thomas, Shay, Jerry W., DeBerardinis, Ralph J., Williams, Noelle S., Yilmaz, Omer H., Conacci-Sorrell, Maralice
發表在 Genes Dev (2019)

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis

由 Padanad, Mahesh S., Konstantinidou, Georgia, Venkateswaran, Niranjan, Melegari, Margherita, Rindhe, Smita, Mitsche, Matthew, Yang, Chendong, Batten, Kimberly, Huffman, Kenneth E., Liu, Jingwen, Tang, Ximing, Rodriguez-Canales, Jaime, Kalhor, Neda, Shay, Jerry W., Minna, John D., McDonald, Jeffrey, Wistuba, Ignacio I., DeBerardinis, Ralph J., Scaglioni, Pier Paolo
發表在 Cell Rep (2016)

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer

由 Kim, Jimi, McMillan, Elizabeth, Kim, Hyun Seok, Venkateswaran, Niranjan, Makkar, Gurbani, Rodriguez-Canales, Jaime, Villalobos, Pamela, Neggers, Jasper Edgar, Mendiratta, Saurabh, Wei, Shuguang, Landesman, Yosef, Senapedis, William, Baloglu, Erkan, Chow, Chi-Wan B., Frink, Robin E., Gao, Boning, Roth, Michael, Minna, John D., Daelemans, Dirk, Wistuba, Ignacio I., Posner, Bruce A., Scaglioni, PierPaolo, White, Michael A.
發表在 Nature (2016)