MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

Tumors display increased uptake and processing of nutrients to fulfill the demands of rapidly proliferating cancer cells. Seminal studies have shown that the proto-oncogene MYC promotes metabolic reprogramming by altering glutamine uptake and metabolism in cancer cells. How MYC regulates the metabol...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Venkateswaran, Niranjan, Lafita-Navarro, M. Carmen, Hao, Yi-Heng, Kilgore, Jessica A., Perez-Castro, Lizbeth, Braverman, Jonathan, Borenstein-Auerbach, Nofit, Kim, Min, Lesner, Nicholas P., Mishra, Prashant, Brabletz, Thomas, Shay, Jerry W., DeBerardinis, Ralph J., Williams, Noelle S., Yilmaz, Omer H., Conacci-Sorrell, Maralice
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719621/
https://ncbi.nlm.nih.gov/pubmed/31416966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.327056.119
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