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MYC-nick promotes cell migration by inducing fascin expression and Cdc42 activation

MYC-nick is a cytoplasmic, transcriptionally inactive member of the MYC oncoprotein family, generated by a proteolytic cleavage of full-length MYC. MYC-nick promotes migration and survival of cells in response to chemotherapeutic agents or withdrawal of glucose. Here we report that MYC-nick is abund...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Anderson, Sarah, Poudel, Kumud Raj, Roh-Johnson, Minna, Brabletz, Thomas, Yu, Ming, Borenstein-Auerbach, Nofit, Grady, William N., Bai, Jihong, Moens, Cecilia B., Eisenman, Robert N., Conacci-Sorrell, Maralice
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027433/
https://ncbi.nlm.nih.gov/pubmed/27566402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610994113
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