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Myc-nick: A cytoplasmic cleavage product of Myc that promotes α-tubulin acetylation and cell differentiation

The Myc oncoprotein family comprises transcription factors that control multiple cellular functions and are widely involved in oncogenesis. Here we report the identification of Myc-nick, a cytoplasmic form of Myc generated by calpain- dependent proteolysis at lysine 298 of full-length Myc. Myc-nick...

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Detalhes bibliográficos
Main Authors: Conacci-Sorrell, Maralice, Ngouenet, Celine, Eisenman, Robert N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923036/
https://ncbi.nlm.nih.gov/pubmed/20691906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.06.037
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