A mass balance approach for calculation of recovery and binding enables the use of ultrafiltration as a rapid method for measurement of plasma protein binding for even highly lipop...

Por Wang, Changguang, Williams, Noelle S.
Publicado em 2012

Synthesis of Psymberin Analogs: Probing a Functional Correlation with the Pederin/Mycalamide Family of Natural Products

Por Jiang, Xin, Williams, Noelle, De Brabander, Jef K.
Publicado em 2007

Lung cancer screening: not all nodules are created equal

Por Shukla, Gaurav, Williams, Noelle L., Luminais, Christopher, Lu, Bo, Shi, Wenyin
Publicado no J Thorac Dis (2016)

RTRB-14 TREATMENT RECOMMENDATIONS FOR ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA LACK WORLDWIDE CONSENSUS

Por Palmer, Joshua, Mehta, Minesh, Williams, Noelle, Dicker, Adam, Werner-Wasik, Maria, Shi, Wenyin
Publicado no Neuro Oncol (2015)

Radioisotopes in management of metastatic prostate cancer

Por Raval, Amar, Dan, Tu D., Williams, Noelle L., Pridjian, Andrew, Den, Robert B.
Publicado no Indian J Urol (2016)

Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity

Por Williams, Noelle S., Burgett, Anthony W. G., Atkins, Ashley S., Wang, Xiaodong, Harran, Patrick G., McKnight, Steven L.
Publicado em 2007

Identification of CREB3L1 as a Biomarker Predicting Doxorubicin Treatment Outcome

Por Denard, Bray, Pavia-Jimenez, Andrea, Chen, Weina, Williams, Noelle S., Naina, Harris, Collins, Robert, Brugarolas, James, Ye, Jin
Publicado no PLoS One (2015)

Development of a triazole class of highly potent Porcn inhibitors

Por You, Lin, Zhang, Chengwei, Yarravarapu, Nageswari, Morlock, Lorraine, Wang, Xiaolei, Zhang, Lishu, Williams, Noelle S., Lum, Lawrence, Chen, Chuo
Publicado no Bioorg Med Chem Lett (2016)

Comparative benefits of Nab-paclitaxel over gemcitabine or polysorbate-based docetaxel in experimental pancreatic cancer

Por Awasthi, Niranjan, Zhang, Changhua, Schwarz, Anna M., Hinz, Stefan, Wang, Changguang, Williams, Noelle S., Schwarz, Margaret A., Schwarz, Roderich E.
Publicado em 2013

Posaconazole, a second-generation triazole antifungal drug, inhibits the Hedgehog signaling pathway and progression of basal cell carcinoma

Por Chen, Baozhi, Trang, Vinh, Lee, Alex, Williams, Noelle S., Wilson, Alexandra N., Epstein, Ervin H., Tang, Jean Y., Kim, James
Publicado no Mol Cancer Ther (2016)

Studies toward the Unique Pederin Family Member Psymberin: Structure Activity Relationships, Biochemical Studies and Genetics Identify the Mode of Action of Psymberin

Por Wu, Cheng-Yang, Feng, Yu, Cardenas, Eduardo R., Williams, Noelle, Floreancig, Paul E., De Brabander, Jef K., Roth, Michael G.
Publicado em 2012

Generation of Lytic Natural Killer 1.1(+), Ly-49(−) Cells from Multipotential Murine Bone Marrow Progenitors in a Stroma-free Culture: Definition of Cytokine Requirements and Devel...

Por Williams, Noelle Sevilir, Moore, Thomas A., Schatzle, John D., Puzanov, Igor J., Sivakumar, P.V., Zlotnik, Albert, Bennett, Michael, Kumar, Vinay
Publicado em 1997

Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy

Por Ma, Xinpeng, Huang, Xiumei, Moore, Zachary, Huang, Gang, Kilgore, Jessica A., Wang, Yiguang, Hammer, Suntrea, Williams, Noelle S., Boothman, David A., Gao, Jinming
Publicado no J Control Release (2014)

Identification of DNMT1 Selective Antagonists Using a Novel Scintillation Proximity Assay

Por Kilgore, Jessica A., Du, Xinlin, Melito, Lisa, Wei, Shuguang, Wang, Changguang, Chin, Hang Gyeong, Posner, Bruce, Pradhan, Sriharsa, Ready, Joseph M., Williams, Noelle S.
Publicado em 2013

Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis

Por Ramadori, Giorgio, Konstantinidou, Georgia, Venkateswaran, Niranjan, Biscotti, Tommasina, Morlock, Lorraine, Galié, Mirco, Williams, Noelle S., Luchetti, Michele, Santinelli, Alfredo, Scaglioni, Pier Paolo, Coppari, Roberto
Publicado no Cell Metab (2015)

Structure/Activity Relationship Studies of Small-Molecule Inhibitors of Wnt Response

Por Lu, Jianming, Ma, Zhiqiang, Hsieh, Jen-Chieh, Fan, Chih-Wei, Chen, Baozhi, Longgood, Jamie C., Williams, Noelle S., Amatruda, James F., Lum, Lawrence, Chen, Chuo
Publicado em 2009

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

Por Derebe, Mehabaw G, Zlatkov, Clare M, Gattu, Sureka, Ruhn, Kelly A, Vaishnava, Shipra, Diehl, Gretchen E, MacMillan, John B, Williams, Noelle S, Hooper, Lora V
Publicado em 2014

Discovery of a Neuroprotective Chemical, (S)-N-(3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(−)-P7C3-S243], with Improved Druglike Properties

Por Naidoo, Jacinth, De Jesus-Cortes, Hector, Huntington, Paula, Estill, Sandi, Morlock, Lorraine K., Starwalt, Ruth, Mangano, Thomas J., Williams, Noelle S., Pieper, Andrew A., Ready, Joseph M.
Publicado em 2014

Smac mimetic increases chemotherapy response and improves survival in mice with pancreatic cancer

Por Dineen, Sean P., Roland, Christina L., Greer, Rachel, Carbon, Juliet G., Toombs, Jason E., Gupta, Puja, Bardeesy, Nabeel, Sun, Haizhou, Williams, Noelle, Minna, John D., Brekken, Rolf A.
Publicado em 2010

High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma

Por Wolff, Nicholas C., Pavía-Jiménez, Andrea, Tcheuyap, Vanina T., Alexander, Shane, Vishwanath, Mridula, Christie, Alana, Xie, Xian-Jin, Williams, Noelle S., Kapur, Payal, Posner, Bruce, McKay, Renée M., Brugarolas, James
Publicado no Oncotarget (2015)