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Synthesis of Psymberin Analogs: Probing a Functional Correlation with the Pederin/Mycalamide Family of Natural Products

[Image: see text] In this communication we describe an efficient synthesis of ‘psympederin’, a hybrid between the novel antitumor natural product psymberin and the blister beetle toxin pederin. Evaluation of antiproliferative activity reveals that the dihydroisocoumarin fragment is important for psy...

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Detalhes bibliográficos
Main Authors: Jiang, Xin, Williams, Noelle, De Brabander, Jef K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631385/
https://ncbi.nlm.nih.gov/pubmed/17217271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062656o
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