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Synthesis of Psymberin Analogs: Probing a Functional Correlation with the Pederin/Mycalamide Family of Natural Products
[Image: see text] In this communication we describe an efficient synthesis of ‘psympederin’, a hybrid between the novel antitumor natural product psymberin and the blister beetle toxin pederin. Evaluation of antiproliferative activity reveals that the dihydroisocoumarin fragment is important for psy...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631385/ https://ncbi.nlm.nih.gov/pubmed/17217271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062656o |
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