Design and Synthesis of TASIN Analogs Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC)

Despite advances in targeted anticancer therapies, there are still no small molecule-based therapies available that specifically target colorectal cancer development and progression, the second-leading cause of cancer deaths. We previously disclosed the discovery of TASIN-1 (Truncating APC-Selective...

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Detaylı Bibliyografya
Yayımlandı:J Med Chem
Asıl Yazarlar: Wang, Wentian, Zhang, Lu, Morlock, Lorraine, Williams, Noelle S., Shay, Jerry W., De Brabander, Jef K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7252524/
https://ncbi.nlm.nih.gov/pubmed/31070915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b00532
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