Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk

While germline mutations in the adenomatous polyposis coli (APC) gene cause the hereditary colon cancer syndrome (Familial Adenomatous Polyposis), the role of common germline APC variants in sporadic adenomatous polyposis remains unclear. We studied the association of eight APC SNPs, possibly associ...

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Bibliografiske detaljer
Main Authors: Wong, Hui-Lee, Peters, Ulrike, Hayes, Richard B., Huang, Wen-Yi, Schatzkin, Arthur, Bresalier, Robert S., Velie, Ellen M., Brody, Lawrence C.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924917/
https://ncbi.nlm.nih.gov/pubmed/20510605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2010.04.020
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