Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk

While germline mutations in the adenomatous polyposis coli (APC) gene cause the hereditary colon cancer syndrome (Familial Adenomatous Polyposis), the role of common germline APC variants in sporadic adenomatous polyposis remains unclear. We studied the association of eight APC SNPs, possibly associ...

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Detalhes bibliográficos
Main Authors: Wong, Hui-Lee, Peters, Ulrike, Hayes, Richard B., Huang, Wen-Yi, Schatzkin, Arthur, Bresalier, Robert S., Velie, Ellen M., Brody, Lawrence C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924917/
https://ncbi.nlm.nih.gov/pubmed/20510605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2010.04.020
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