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Design and Synthesis of TASIN Analogs Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC)
Despite advances in targeted anticancer therapies, there are still no small molecule-based therapies available that specifically target colorectal cancer development and progression, the second-leading cause of cancer deaths. We previously disclosed the discovery of TASIN-1 (Truncating APC-Selective...
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| Publicado no: | J Med Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7252524/ https://ncbi.nlm.nih.gov/pubmed/31070915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b00532 |
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