Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner

Por Frink, Robin E., Peyton, Michael, Schiller, Joan H., Gazdar, Adi F., Shay, Jerry W., Minna, John D.
Publicado no Oncotarget (2016)

Cancer-specific production of N-acetylaspartate via NAT8L overexpression in non-small cell lung cancer and its potential as a circulating biomarker

Por Lou, Tzu-Fang, Sethuraman, Deepa, Dospoy, Patrick, Srivastva, Pallevi, Kim, Hyun Seok, Kim, Joongsoo, Ma, Xiaotu, Chen, Pei-Hsuan, Huffman, Kenneth E., Frink, Robin E., Larsen, Jill E., Lewis, Cheryl, Um, Sang-Won, Kim, Duk-Hwan, Ahn, Jung-Mo, DeBerardinis, Ralph J., White, Michael A., Minna, John D., Yoo, Hyuntae
Publicado no Cancer Prev Res (Phila) (2015)

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer

Por Kim, Jimi, McMillan, Elizabeth, Kim, Hyun Seok, Venkateswaran, Niranjan, Makkar, Gurbani, Rodriguez-Canales, Jaime, Villalobos, Pamela, Neggers, Jasper Edgar, Mendiratta, Saurabh, Wei, Shuguang, Landesman, Yosef, Senapedis, William, Baloglu, Erkan, Chow, Chi-Wan B., Frink, Robin E., Gao, Boning, Roth, Michael, Minna, John D., Daelemans, Dirk, Wistuba, Ignacio I., Posner, Bruce A., Scaglioni, PierPaolo, White, Michael A.
Publicado no Nature (2016)