Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

Por Tomimatsu, Nozomi, Mukherjee, Bipasha, Hardebeck, Molly Catherine, Ilcheva, Mariya, Camacho, Cristel Vanessa, Harris, Janelle Louise, Porteus, Matthew, Llorente, Bertrand, Khanna, Kum Kum, Burma, Sandeep
Publicado em 2014

Focal Adhesion Kinase regulates the DNA damage response and its inhibition radiosensitizes mutant KRAS lung cancer

Por Tang, Ke-Jing, Constanzo, Jerfiz, Venkateswaran, Niranjan, Melegari, Margherita, Ilcheva, Mariya, Morales, Julio C., Skoulidis, Ferdinandos, Heymach, John V., Boothman, David A., Scaglioni, Pier Paolo
Publicado no Clin Cancer Res (2016)

Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone

Por Chakrabarti, Gaurab, Silvers, Molly A., Ilcheva, Mariya, Liu, Yuliang, Moore, Zachary R., Luo, Xiuquan, Gao, Jinming, Anderson, Glenda, Liu, Lili, Sarode, Venetia, Gerber, David E., Burma, Sandeep, DeBerardinis, Ralph J., Gerson, Stanton L., Boothman, David A.
Publicado no Sci Rep (2015)

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone

Por Chakrabarti, Gaurab, Moore, Zachary R., Luo, Xiuquan, Ilcheva, Mariya, Ali, Aktar, Padanad, Mahesh, Zhou, Yunyun, Xie, Yang, Burma, Sandeep, Scaglioni, Pier P., Cantley, Lewis C., DeBerardinis, Ralph J., Kimmelman, Alec C., Lyssiotis, Costas A., Boothman, David A.
Publicado no Cancer Metab (2015)

DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification

Por Camacho, Cristel V., Todorova, Pavlina K., Gillam, Molly C., Tomimatsu, Nozomi, del Alcazar, Carlos R Gil, Ilcheva, Mariya, Mukherjee, Bipasha, McEllin, Brian, Vemireddy, Vamsidhara, Hatanpaa, Kimmo, Story, Michael D., Habib, Amyn A., Murty, Vundavalli V., Bachoo, Robert, Burma, Sandeep
Publicado em 2014