Co-occurring genomic alterations in non-small cell lung cancer biology and therapy

Bằng Skoulidis, Ferdinandos, Heymach, John V.
Xuất bản năm Nat Rev Cancer (2019)

Penicillium marneffei: a pathogen on our doorstep?

Bằng Skoulidis, Ferdinandos, Morgan, Marina S, MacLeod, Kenneth M
Được phát hành 2004

Context dependence of Checkpoint kinase 1 as a therapeutic target for pancreatic cancers deficient in the BRCA2 tumour suppressor

Bằng Hattori, Hiroyoshi, Skoulidis, Ferdinandos, Russell, Paul, Venkitaraman, Ashok R.
Được phát hành 2011

Focal Adhesion Kinase regulates the DNA damage response and its inhibition radiosensitizes mutant KRAS lung cancer

Bằng Tang, Ke-Jing, Constanzo, Jerfiz, Venkateswaran, Niranjan, Melegari, Margherita, Ilcheva, Mariya, Morales, Julio C., Skoulidis, Ferdinandos, Heymach, John V., Boothman, David A., Scaglioni, Pier Paolo
Xuất bản năm Clin Cancer Res (2016)

LKB1/STK11 Expression in Lung Adenocarcinoma and Associations with Patterns of Recurrence

Bằng Mitchell, Kyle G., Parra, Edwin R., Zhang, Jiexin, Nelson, David B., Corsini, Erin M., Villalobos, Pamela, Moran, Cesar A., Skoulidis, Ferdinandos, Wistuba, Ignacio I., Fujimoto, Junya, Roth, Jack A., Antonoff, Mara B.
Xuất bản năm Ann Thorac Surg (2020)

A patient-derived, pan-cancer EMT signature identifies global molecular alterations and immune target enrichment following epithelial to mesenchymal transition

Bằng Mak, Milena P., Tong, Pan, Diao, Lixia, Cardnell, Robert J., Gibbons, Don L., William, William N., Skoulidis, Ferdinandos, Parra, Edwin R., Rodriguez-Canales, Jaime, Wistuba, Ignacio I., Heymach, John V., Weinstein, John N., Coombes, Kevin R., Wang, Jing, Byers, Lauren Averett
Xuất bản năm Clin Cancer Res (2015)

Simplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations

Bằng Ruiz-Cordero, Roberto, Ma, Junsheng, Khanna, Abha, Lyons, Genevieve, Rinsurongkawong, Waree, Bassett, Roland, Guo, Ming, Routbort, Mark J., Zhang, Jianjun, Skoulidis, Ferdinandos, Heymach, John, Roarty, Emily B., Tang, Zhenya, Medeiros, L. Jeffrey, Patel, Keyur P., Luthra, Rajyalakshmi, Roy-Chowdhuri, Sinchita
Xuất bản năm BMC Cancer (2020)

Pembrolizumab with or without radiation therapy for metastatic non-small cell lung cancer: a randomized phase I/II trial

Bằng Welsh, James, Menon, Hari, Chen, Dawei, Verma, Vivek, Tang, Chad, Altan, Mehmet, Hess, Kenneth, de Groot, Patricia, Nguyen, Quynh-Nhu, Varghese, Rejani, Comeaux, Nathan I, Simon, George, Skoulidis, Ferdinandos, Chang, Joe Y, Papdimitrakopoulou, Vasiliki, Lin, Steven H, Heymach, John V
Xuất bản năm J Immunother Cancer (2020)

LKB1 and KEAP1/NRF2 pathways cooperatively promote metabolic reprogramming with enhanced glutamine dependence in KRAS-mutant lung adenocarcinoma

Bằng Galan-Cobo, Ana, Sitthideatphaiboon, Piyada, Qu, Xiao, Poteete, Alissa, Pisegna, Marlese A., Tong, Pan, Chen, Pei-Hsuan, Boroughs, Lindsey K., Rodriguez, Mirna L.M., Zhang, Winter, Parlati, Francesco, Wang, Jing, Gandhi, Varsha, Skoulidis, Ferdinandos, DeBerardinis, Ralph J., Minna, John D., Heymach, John V.
Xuất bản năm Cancer Res (2019)

Bone morphogenetic protein 7 promotes resistance to immunotherapy

Bằng Cortez, Maria Angelica, Masrorpour, Fatemeh, Ivan, Cristina, Zhang, Jie, Younes, Ahmed, Lu, Yue, Estecio, Marcos R, Barsoumian, Hampartsoum B., Menon, Hari, Caetano, Mauricio da Silva, Ramapriyan, Rishab, Schoenhals, Jonathan E., Wang, Xiaohong, Skoulidis, Ferdinandos, Wasley, Mark D., Calin, George, Hwu, Patrick, Welsh, James W.
Xuất bản năm Nat Commun (2020)

Author Correction: Bone morphogenetic protein 7 promotes resistance to immunotherapy

Bằng Cortez, Maria Angelica, Masrorpour, Fatemeh, Ivan, Cristina, Zhang, Jie, Younes, Ahmed I., Lu, Yue, Estecio, Marcos R., Barsoumian, Hampartsoum B., Menon, Hari, da Silva Caetano, Mauricio, Ramapriyan, Rishab, Schoenhals, Jonathan E., Wang, Xiaohong, Skoulidis, Ferdinandos, Wasley, Mark D., Calin, George, Hwu, Patrick, Welsh, James W.
Xuất bản năm Nat Commun (2020)

De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer

Bằng Singh, Anju, Ruiz, Christian, Bhalla, Kavita, Haley, John A., Li, Qing Kay, Acquaah-Mensah, George, Montal, Emily, Sudini, Kuladeep R., Skoulidis, Ferdinandos, Wistuba, Ignacio I., Papadimitrakopoulou, Vassiliki, Heymach, John V., Boros, Laszlo G., Gabrielson, Edward, Carretero, Julian, Wong, Kwok-Kin, Haley, John D., Biswal, Shyam, Girnun, Geoffrey D.
Xuất bản năm FASEB J (2018)

Local Consolidative Therapy Vs. Maintenance Therapy or Observation for Patients With Oligometastatic Non–Small-Cell Lung Cancer: Long-Term Results of a Multi-Institutional, Phase I...

Bằng Gomez, Daniel R., Tang, Chad, Zhang, Jianjun, Blumenschein, George R., Hernandez, Mike, Lee, J. Jack, Ye, Rong, Palma, David A., Louie, Alexander V., Camidge, D. Ross, Doebele, Robert C., Skoulidis, Ferdinandos, Gaspar, Laurie E., Welsh, James W., Gibbons, Don L., Karam, Jose A., Kavanagh, Brian D., Tsao, Anne S., Sepesi, Boris, Swisher, Stephen G., Heymach, John V.
Xuất bản năm J Clin Oncol (2019)

Local Consolidative Therapy versus Maintenance Therapy/Observation for Patients with Oligometastatic Non-Small Cell Lung Cancer without Progression after Front-Line Systemic Therap...

Bằng Gomez, Daniel R., Blumenschein, George R., Lee, J. Jack, Hernandez, Mike, Ye, Rong, Camidge, D. Ross, Doebele, Robert C., Skoulidis, Ferdinandos, Gaspar, Laurie E., Gibbons, Don L., Karam, Jose A., Kavanagh, Brian D., Tang, Chad, Komaki, Ritsuko, Louie, Alexander V., Palma, David A., Tsao, Anne S., Sepesi, Boris, William, William N., Zhang, Jianjun, Shi, Qiuling, Wang, Xin Shelley, Swisher, Stephen G., Heymach, John V.
Xuất bản năm Lancet Oncol (2016)

STING pathway expression identifies non-small cell lung cancers with an immune-responsive phenotype

Bằng Corte, Carminia M. Della, Sen, Triparna, Gay, Carl M., Ramkumar, Kavya, Diao, Lixia, Cardnell, Robert J., Rodriguez, B. Leticia, Stewart, C. Allison, Papadimitrakopoulou, Vassiliki A., Gibson, Laura, Fradette, Jared J., Wang, Qi, Fan, Youhong, Peng, David H., Negrao, Marcelo V., Witsuba, Ignacio I., Fujimoto, Junya, Soto, Luisa M. Solis, Behrens, Carmen, Skoulidis, Ferdinandos, Heymach, John V., Wang, Jing, Gibbons, Don L., Byers, Lauren A.
Xuất bản năm J Thorac Oncol (2020)

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer

Bằng Papadimitrakopoulou, Vassiliki, Lee, J. Jack, Wistuba, Ignacio I., Tsao, Anne S., Fossella, Frank V., Kalhor, Neda, Gupta, Sanjay, Byers, Lauren Averett, Izzo, Julie G., Gettinger, Scott N., Goldberg, Sarah B., Tang, Ximing, Miller, Vincent A., Skoulidis, Ferdinandos, Gibbons, Don L., Shen, Li, Wei, Caimiao, Diao, Lixia, Peng, S. Andrew, Wang, Jing, Tam, Alda L., Coombes, Kevin R., Koo, Ja Seok, Mauro, David J., Rubin, Eric H., Heymach, John V., Hong, Waun Ki, Herbst, Roy S.
Xuất bản năm J Clin Oncol (2016)

STK11/LKB1 deficiency promotes neutrophil recruitment and proinflammatory cytokine production to suppress T cell activity in the lung tumor microenvironment

Bằng Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Aref, Amir R., Skoulidis, Ferdinandos, Herter-Sprie, Grit S., Buczkowski, Kevin A., Liu, Yan, Awad, Mark M., Denning, Warren L., Diao, Lixia, Wang, Jing, Parra-Cuentas, Edwin R., Wistuba, Ignacio I., Soucheray, Margaret, Thai, Tran C., Asahina, Hajime, Kitajima, Shunsuke, Altabef, Abigail, Cavanaugh, Jillian D., Rhee, Kevin, Gao, Peng, Zhang, Haikuo, Fecci, Peter E., Shimamura, Takeshi, Hellmann, Matthew D., Heymach, John V., Hodi, F. Stephen, Freeman, Gordon J., Barbie, David A., Dranoff, Glenn, Hammerman, Peter S., Wong, Kwok-Kin
Xuất bản năm Cancer Res (2016)

Co-occurring genomic alterations define major subsets of KRAS - mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

Bằng Skoulidis, Ferdinandos, Byers, Lauren A., Diao, Lixia, Papadimitrakopoulou, Vassiliki A., Tong, Pan, Izzo, Julie, Behrens, Carmen, Kadara, Humam, Parra, Edwin R., Canales, Jaime Rodriguez, Zhang, Jianjun, Giri, Uma, Gudikote, Jayanthi, Cortez, Maria A., Yang, Chao, Fan, You Hong, Peyton, Michael, Girard, Luc, Coombes, Kevin R., Toniatti, Carlo, Heffernan, Timothy P., Choi, Murim, Frampton, Garrett M., Miller, Vincent, Weinstein, John N., Herbst, Roy S., Wong, Kwok-Kin, Zhang, Jianhua, Sharma, Padmanee, Mills, Gordon B., Hong, Waun K., Minna, John D., Allison, James P., Futreal, Andrew, Wang, Jing, Wistuba, Ignacio I., Heymach, John V.
Xuất bản năm Cancer Discov (2015)

CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-L1 blockade

Bằng Chen, Limo, Diao, Lixia, Yang, Yongbin, Yi, Xiaohui, Leticia Rodriguez, B., Li, Yanli, Villalobos, Pamela A., Cascone, Tina, Liu, Xi, Tan, Lin, Lorenzi, Philip L., Huang, Anfei, Zhao, Qiang, Peng, Di, Fradette, Jared J., Peng, David H., Ungewiss, Christin, Roybal, Jonathon, Tong, Pan, Oba, Junna, Skoulidis, Ferdinandos, Peng, Weiyi, Carter, Brett W., Gay, Carl M., Fan, Youhong, Class, Caleb A., Zhu, Jingfen, Rodriguez-Canales, Jaime, Kawakami, Masanori, Averett Byers, Lauren, Woodman, Scott E., Papadimitrakopoulou, Vassiliki A., Dmitrovsky, Ethan, Wang, Jing, Ullrich, Stephen E., Wistuba, Ignacio I., Heymach, John V., Xiao-Feng Qin, F., Gibbons, Don L.
Xuất bản năm Cancer Discov (2018)

STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma

Bằng Skoulidis, Ferdinandos, Goldberg, Michael E., Greenawalt, Danielle M., Hellmann, Matthew D., Awad, Mark M., Gainor, Justin F., Schrock, Alexa B., Hartmaier, Ryan J., Trabucco, Sally E., Gay, Laurie, Ali, Siraj M., Elvin, Julia A., Singal, Gaurav, Ross, Jeffrey S., Fabrizio, David, Szabo, Peter M., Chang, Han, Sasson, Ariella, Srinivasan, Sujaya, Kirov, Stefan, Szustakowski, Joseph, Vitazka, Patrik, Edwards, Robin, Bufill, Jose A., Sharma, Neelesh, Ou, Sai-Hong I., Peled, Nir, Spigel, David R., Rizvi, Hira, Aguilar, Elizabeth Jimenez, Carter, Brett W., Erasmus, Jeremy, Halpenny, Darragh F., Plodkowski, Andrew J., Long, Niamh M., Nishino, Mizuki, Denning, Warren L., Galan-Cobo, Ana, Hamdi, Haifa, Hirz, Taghreed, Tong, Pan, Wang, Jing, Rodriguez-Canales, Jaime, Villalobos, Pamela A., Parra, Edwin R., Kalhor, Neda, Sholl, Lynette M., Sauter, Jennifer L., Jungbluth, Achim A., Mino-Kenudson, Mari, Azimi, Roxana, Elamin, Yasir Y., Zhang, Jianjun, Leonardi, Giulia C., Jiang, Fei, Wong, Kwok-Kin, Lee, J. Jack, Papadimitrakopoulou, Vassiliki A., Wistuba, Ignacio I., Miller, Vincent A., Frampton, Garrett M., Wolchok, Jedd D., Shaw, Alice T., Jänne, Pasi A., Stephens, Philip J., Rudin, Charles M., Geese, William J., Albacker, Lee A., Heymach, John V.
Xuất bản năm Cancer Discov (2018)