Bone morphogenetic protein 7 promotes resistance to immunotherapy

Immunotherapies revolutionized cancer treatment by harnessing the immune system to target cancer cells. However, most patients are resistant to immunotherapies and the mechanisms underlying this resistant is still poorly understood. Here, we report that overexpression of BMP7, a member of the TGFB s...

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Pubblicato in:Nat Commun
Autori principali: Cortez, Maria Angelica, Masrorpour, Fatemeh, Ivan, Cristina, Zhang, Jie, Younes, Ahmed, Lu, Yue, Estecio, Marcos R, Barsoumian, Hampartsoum B., Menon, Hari, Caetano, Mauricio da Silva, Ramapriyan, Rishab, Schoenhals, Jonathan E., Wang, Xiaohong, Skoulidis, Ferdinandos, Wasley, Mark D., Calin, George, Hwu, Patrick, Welsh, James W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519103/
https://ncbi.nlm.nih.gov/pubmed/32973129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18617-z
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