Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer

Por Cardnell, Robert J., Feng, Ying, Mukherjee, Seema, Diao, Lixia, Tong, Pan, Stewart, C. Allison, Masrorpour, Fatemeh, Fan, YouHong, Nilsson, Monique, Shen, Yuqiao, Heymach, John V., Wang, Jing, Byers, Lauren A.
Publicado no PLoS One (2016)

AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers

Por Balaji, Kavitha, Vijayaraghavan, Smruthi, Diao, Lixia, Tong, Pan, Fan, Youhong, Carey, Jason PW, Bui, Tuyen N., Warner, Steve, Heymach, John V, Hunt, Kelly K, Wang, Jing, Byers, Lauren Averett, Keyomarsi, Khandan
Publicado no Mol Cancer Res (2016)

An integrated molecular analysis of lung adenocarcinomas identifies potential therapeutic targets among TTF1-negative tumors including DNA repair proteins and Nrf2

Por Cardnell, Robert J.G., Behrens, Carmen, Diao, Lixia, Fan, YouHong, Tang, Ximing, Tong, Pan, John D., Minna, Mills, Gordon B., Heymach, John V., Wistuba, Ignacio I., Wang, Jing, Byers., Lauren A.
Publicado no Clin Cancer Res (2015)

Epithelial-mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung adenocarc...

Por Lou, Yanyan, Diao, Lixia, Cuentas, Edwin Roger Parra, Denning, Warren L., Chen, Limo, Fan, Youhong, Byers, Lauren A., Wang, Jing, Papadimitrakopoulou, Vassiliki, Behrens, Carmen, Rodriguez, Jaime Canales, Hwu, Patrick, Wistuba, Ignacio I., Heymach, John V., Gibbons, Don L.
Publicado no Clin Cancer Res (2016)

KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib

Por Nilsson, Monique B., Giri, Uma, Gudikote, Jayanthi, Tang, Ximing, Lu, Wei, Tran, Hai, Fan, Youhong, Koo, Andrew, Diao, Lixia, Tong, Pan, Wang, Jing, Herbst, Roy, Johnson, Bruce E., Ryan, Andy, Webster, Alan, Rowe, Philip, Wistuba, Ignacio I., Heymach, John V.
Publicado no Clin Cancer Res (2015)

An epithelial-mesenchymal transition (EMT) gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor r...

Por Byers, Lauren Averett, Diao, Lixia, Wang, Jing, Saintigny, Pierre, Girard, Luc, Peyton, Mike, Shen, Li, Fan, Youhong, Giri, Uma, Tumula, Praveen K., Nilsson, Monique B., Gudikote, Jayanthi, Tran, Hai, Cardnell, Robert J.G., Bearss, David J., Warner, Steven L., Foulks, Jason M., Kanner, Steven B., Gandhi, Varsha, Krett, Nancy, Rosen, Steven T., Kim, Edward S., Herbst, Roy S., Blumenschein, George R., Lee, J. Jack, Lippman, Scott M., Ang, Kian, Mills, Gordon B., Hong, Waun K., Weinstein, John N., Wistuba, Ignacio I., Coombes, Kevin R., Minna, John D., Heymach, John V.
Publicado em 2012