Pdx-1-Driven Overexpression of Aurora A Kinase Induces Mild Ductal Dyplasia of Pancreatic Ducts Near Islets in Transgenic Mice

Por Warner, Steven L., Muñoz, Ruben M., Bearss, David J., Grippo, Paul, Han, Haiyong, Von Hoff, Daniel D.
Publicado em 2008

Axl Activates Fibroblast Growth Factor Receptor Pathway to Potentiate Survival Signals in B-Cell Chronic Lymphocytic Leukemia Cells

Por Sinha, Sutapa, Boysen, Justin, Nelson, Michael, Warner, Steven L., Bearss, David, Kay, Neil E., Ghosh, Asish K.
Publicado no Leukemia (2015)

Inhibition of Nek2 by Small Molecules Affects Proteasome Activity

Por Meng, Lingyao, Carpenter, Kent, Mollard, Alexis, Vankayalapati, Hariprasad, Warner, Steven L., Sharma, Sunil, Tricot, Guido, Zhan, Fenghuang, Bearss, David J.
Publicado em 2014

Design, Synthesis, and Biological Evaluation of a Series of Novel AXL Kinase Inhibitors

Por Mollard, Alexis, Warner, Steven L., Call, Lee T., Wade, Mark L., Bearss, Jared J., Verma, Anupam, Sharma, Sunil, Vankayalapati, Hariprasad, Bearss, David J.
Publicado em 2011

Validation of TPX2 as a Potential Therapeutic Target in Pancreatic Cancer Cells

Por Warner, Steven L., Stephens, Bret J., Nwokenkwo, Stanley, Hostetter, Galen, Sugeng, Anastasia, Hidalgo, Manuel, Trent, Jeffery M., Han, Haiyong, Von Hoff, Daniel D.
Publicado em 2009

S110, a 5-aza-2’-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth

Por Chuang, Jody C., Warner, Steven L., Vollmer, David, Vankayalapati, Hariprasad, Redkar, Sanjeev, Bearss, David J., Qiu, Xiangning, Yoo, Christine B., Jones, Peter A.
Publicado em 2010

The Tumor Suppressor Axis p53/miR-34a Regulates Axl Expression in B-Cell Chronic Lymphocytic Leukemia: Implications for Therapy in p53-Defective CLL Patients

Por Boysen, Justin, Sinha, Sutapa, Price-Troska, Tammy, Warner, Steven L., Bearss, David J., Viswanatha, David, Shanafelt, Tait D., Kay, Neil E., Ghosh, Asish K.
Publicado em 2013

Axl Inhibition Primes Chronic Lymphocytic Leukemia B-Cells to Apoptosis and Show Synergistic/Additive Effects in Combination with BTK inhibitors

Por Sinha, Sutapa, Boysen, Justin, Nelson, Michael, Secreto, Charla, Warner, Steven L., Bearss, David J., Lesnick, Connie, Shanafelt, Tait D., Kay, Neil E., Ghosh, Asish K.
Publicado no Clin Cancer Res (2015)

TIG1 Promotes the Development and Progression of Inflammatory Breast Cancer through Activation of Axl Kinase

Por Wang, Xiaoping, Saso, Hitomi, Iwamoto, Takayuki, Xia, Weiya, Gong, Yun, Pusztai, Lajos, Woodward, Wendy A., Reuben, James M., Warner, Steven L., Bearss, David J., Hortobagyi, Gabriel N., Hung, Mien-Chie, Ueno, Naoto T.
Publicado no Cancer Res (2013)

Upregulation of AXL and β-catenin in chronic lymphocytic leukemia cells cultured with bone marrow stroma cells is associated with enhanced drug resistance

Por Sinha, Sutapa, Secreto, Charla R., Boysen, Justin C., Lesnick, Connie, Wang, Zhiquan, Ding, Wei, Call, Timothy G., Kenderian, Saad J., Parikh, Sameer A., Warner, Steven L., Bearss, David J., Ghosh, Asish K., Kay, Neil E.
Publicado no Blood Cancer J (2021)

Mitochondrial Priming of Chronic Lymphocytic Leukemia Patients Associates Bcl-x(L) Dependence with Alvocidib Response

Por Pierceall, William E., Warner, Steven L., Lena, Ryan J., Doykan, Camille, Blake, Noel, Elashoff, Michael, Von Hoff, Daniel, Bearss, David J., Cardone, Michael H., Andritsos, Leslie, Byrd, John C., Lanasa, Mark C., Grever, Michael R., Johnson, Amy J.
Publicado no Leukemia (2014)

Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy

Por Sinha, Sutapa, Boysen, Justin C., Chaffee, Kari G., Kabat, Brian F., Slager, Susan L., Parikh, Sameer A., Secreto, Charla R., Call, Tim, Shanafelt, Tait D., Leis, Jose F., Warner, Steven L., Bearss, David J., Ghosh, Asish K., Kay, Neil E.
Publicado no Oncotarget (2018)

A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas()()

Por Foulks, Jason M., Carpenter, Kent J., Luo, Bai, Xu, Yong, Senina, Anna, Nix, Rebecca, Chan, Ashley, Clifford, Adrianne, Wilkes, Marcus, Vollmer, David, Brenning, Benjamin, Merx, Shannon, Lai, Shuping, McCullar, Michael V., Ho, Koc-Kan, Albertson, Daniel J., Call, Lee T., Bearss, Jared J., Tripp, Sheryl, Liu, Ting, Stephens, Bret J., Mollard, Alexis, Warner, Steven L., Bearss, David J., Kanner, Steven B.
Publicado em 2014

An epithelial-mesenchymal transition (EMT) gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor r...

Por Byers, Lauren Averett, Diao, Lixia, Wang, Jing, Saintigny, Pierre, Girard, Luc, Peyton, Mike, Shen, Li, Fan, Youhong, Giri, Uma, Tumula, Praveen K., Nilsson, Monique B., Gudikote, Jayanthi, Tran, Hai, Cardnell, Robert J.G., Bearss, David J., Warner, Steven L., Foulks, Jason M., Kanner, Steven B., Gandhi, Varsha, Krett, Nancy, Rosen, Steven T., Kim, Edward S., Herbst, Roy S., Blumenschein, George R., Lee, J. Jack, Lippman, Scott M., Ang, Kian, Mills, Gordon B., Hong, Waun K., Weinstein, John N., Wistuba, Ignacio I., Coombes, Kevin R., Minna, John D., Heymach, John V.
Publicado em 2012