Cargando...

Pdx-1-Driven Overexpression of Aurora A Kinase Induces Mild Ductal Dyplasia of Pancreatic Ducts Near Islets in Transgenic Mice

OBJECTIVES: To further explore the oncogenic activity of Aurora A kinase while attempting to develop a useful mouse model for pancreatic cancer, Aurora A kinase was targeted to Pdx-1 positive cells. METHODS: Aurora A kinase overexpression was targeted to mouse pancreas tissue using the Pdx-1 promote...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Warner, Steven L., Muñoz, Ruben M., Bearss, David J., Grippo, Paul, Han, Haiyong, Von Hoff, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728596/
https://ncbi.nlm.nih.gov/pubmed/18815537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e318176b9ae
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!