Generation of Islet-like Cell Aggregates from Human Adipose Tissue-derived Stem Cells by Lentiviral Overexpression of PDX-1

BACKGROUND: Pancreatic duodenal homeobox1 (PDX-1) is a transcription factor that is important in regulating pancreas development and maintaining β-cell function. β-cell replacement is an effective approach for the treatment of type 1 diabetes. Human adipose-mesenchymal stem cells (hAMSCs) are the id...

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Veröffentlicht in:Int J Organ Transplant Med
Hauptverfasser: Bahrebar, M., Soleimani, M., Karimi, M. H., Vahdati, A., Yaghobi, R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Avicenna Organ Transplantation Institute 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464280/
https://ncbi.nlm.nih.gov/pubmed/26082830
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