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A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas()()

The proto-oncogene proviral integration site for moloney murine leukemia virus (PIM) kinases (PIM-1, PIM-2, and PIM-3) are serine/threonine kinases that are involved in a number of signaling pathways important to cancer cells. PIM kinases act in downstream effector functions as inhibitors of apoptos...

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Detalhes bibliográficos
Main Authors: Foulks, Jason M., Carpenter, Kent J., Luo, Bai, Xu, Yong, Senina, Anna, Nix, Rebecca, Chan, Ashley, Clifford, Adrianne, Wilkes, Marcus, Vollmer, David, Brenning, Benjamin, Merx, Shannon, Lai, Shuping, McCullar, Michael V., Ho, Koc-Kan, Albertson, Daniel J., Call, Lee T., Bearss, Jared J., Tripp, Sheryl, Liu, Ting, Stephens, Bret J., Mollard, Alexis, Warner, Steven L., Bearss, David J., Kanner, Steven B.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198696/
https://ncbi.nlm.nih.gov/pubmed/24953177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.05.004
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