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AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers

Epithelial to mesenchymal transition (EMT) is associated with a wide range of changes in cancer cells, including stemness, chemo- and radio-resistance and metastasis. The mechanistic role of upstream mediators of EMT has not yet been well characterized. Recently, we showed that non-small cell lung c...

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Publicat a:Mol Cancer Res
Autors principals: Balaji, Kavitha, Vijayaraghavan, Smruthi, Diao, Lixia, Tong, Pan, Fan, Youhong, Carey, Jason PW, Bui, Tuyen N., Warner, Steve, Heymach, John V, Hunt, Kelly K, Wang, Jing, Byers, Lauren Averett, Keyomarsi, Khandan
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215967/
https://ncbi.nlm.nih.gov/pubmed/27671334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0157
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