Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis

Dietary effects on tumor biology can be exploited to unravel cancer vulnerabilities. Here, we present surprising evidence for anti-proliferative action of high-calorie-diet (HCD) feeding on KRAS-driven lung tumors. Tumors of mice that commenced HCD feeding before tumor onset displayed defective unfo...

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Bibliografiska uppgifter
I publikationen:Cell Metab
Huvudupphovsmän: Ramadori, Giorgio, Konstantinidou, Georgia, Venkateswaran, Niranjan, Biscotti, Tommasina, Morlock, Lorraine, Galié, Mirco, Williams, Noelle S., Luchetti, Michele, Santinelli, Alfredo, Scaglioni, Pier Paolo, Coppari, Roberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2015
Ämnen:
Short Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305190/
https://ncbi.nlm.nih.gov/pubmed/25533479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.11.020
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