RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven adenocarcinomas

Non-small cell lung cancer (NSCLC) often expresses mutant KRAS together with tumor-associated mutations of the CDKN2A locus, which are associated with aggressive, therapy-resistant tumors. Here, we unravel specific requirements for the maintenance of NSCLC that carry this genotype. We establish that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Konstantinidou, Georgia, Ramadori, Giorgio, Torti, Francesca, Kangasniemi, Kim, Ramirez, Rachel E., Cai, Yiran, Behrens, Carmen, Dellinger, Michael T., Brekken, Rolf A., Wistuba, Ignacio I., Heguy, Adriana, Teruya-Feldstein, Julie, Scaglioni, Pier Paolo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625467/
https://ncbi.nlm.nih.gov/pubmed/23358651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0388
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak