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Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis
Dietary effects on tumor biology can be exploited to unravel cancer vulnerabilities. Here, we present surprising evidence for anti-proliferative action of high-calorie-diet (HCD) feeding on KRAS-driven lung tumors. Tumors of mice that commenced HCD feeding before tumor onset displayed defective unfo...
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| Veröffentlicht in: | Cell Metab |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4305190/ https://ncbi.nlm.nih.gov/pubmed/25533479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.11.020 |
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