The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy

Cells continually assess their energy and nutrient state to maintain growth and survival and engage necessary homeostatic mechanisms. Cell autonomous responses to the fed state require the surveillance of the availability of amino acids and other nutrients. The mammalian target of rapamycin complex...

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Hauptverfasser: Wauson, Eric M., Zaganjor, Elma, Lee, A-Young, Guerra, Marcy L., Ghosh, Anwesha B., Bookout, Angie L., Chambers, Chris P., Jivan, Arif, McGlynn, Kathleen, Hutchison, Michele R., Deberardinis, Ralph J., Cobb, Melanie H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749915/
https://ncbi.nlm.nih.gov/pubmed/22959271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.001
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