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mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors
The mechanistic target of rapamycin complex 1 (mTORC1) has been reported to be necessary for metabotropic glutamate receptor-mediated long-term depression (mGluR-LTD). Here we found that mTORC1-deficient mice exhibit normal hippocampal mGluR-LTD and associated behaviors. Moreover, rapamycin blocks m...
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| Publicado en: | Nat Neurosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467217/ https://ncbi.nlm.nih.gov/pubmed/29786082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0156-7 |
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