Genetically-defined metabolic reprogramming in cancer

Por Mullen, Andrew R., DeBerardinis, Ralph J.
Publicado em 2012

Metabolic changes in cancer cells upon suppression of MYC

Por Anso, Elena, Mullen, Andrew R, Felsher, Dean W, Matés, José M, DeBerardinis, Ralph J, Chandel, Navdeep S
Publicado em 2013

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

Por Cheng, Tzuling, Sudderth, Jessica, Yang, Chendong, Mullen, Andrew R., Jin, Eunsook S., Matés, José M., DeBerardinis, Ralph J.
Publicado em 2011

The proto-oncometabolite fumarate binds glutathione to amplify ROS dependent signaling

Por Sullivan, Lucas B., Garcia-Martinez, Eva, Nguyen, Hien, Mullen, Andrew R., Dufour, Eric, Sudarshan, Sunil, Licht, Jonathan D., Deberardinis, Ralph J., Chandel, Navdeep S.
Publicado em 2013

Reductive carboxylation supports growth in tumor cells with defective mitochondria

Por Mullen, Andrew R., Wheaton, William W., Jin, Eunsook S., Chen, Pei-Hsuan, Sullivan, Lucas B., Cheng, Tzuling, Yang, Youfeng, Linehan, W. Marston, Chandel, Navdeep S., DeBerardinis, Ralph J.
Publicado em 2011

Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

Por Hamanaka, Robert B., Glasauer, Andrea, Hoover, Paul, Yang, Shuangni, Blatt, Hanz, Mullen, Andrew R., Getsios, Spiro, Gottardi, Cara J., DeBerardinis, Ralph J., Lavker, Robert M., Chandel, Navdeep S.
Publicado em 2013

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects

Por Mullen, Andrew R., Hu, Zeping, Shi, Xiaolei, Jiang, Lei, Boroughs, Lindsey K., Kovacs, Zoltan, Boriack, Richard, Rakheja, Dinesh, Sullivan, Lucas B., Linehan, W. Marston, Chandel, Navdeep S., DeBerardinis, Ralph J.
Publicado em 2014