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Metabolic changes in cancer cells upon suppression of MYC

BACKGROUND: Cancer cells engage in aerobic glycolysis and glutaminolysis to fulfill their biosynthetic and energetic demands in part by activating MYC. Previous reports have characterized metabolic changes in proliferating cells upon MYC loss or gain of function. However, metabolic differences betwe...

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Detalhes bibliográficos
Main Authors: Anso, Elena, Mullen, Andrew R, Felsher, Dean W, Matés, José M, DeBerardinis, Ralph J, Chandel, Navdeep S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178210/
https://ncbi.nlm.nih.gov/pubmed/24280108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-7
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