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Metabolic changes in cancer cells upon suppression of MYC

BACKGROUND: Cancer cells engage in aerobic glycolysis and glutaminolysis to fulfill their biosynthetic and energetic demands in part by activating MYC. Previous reports have characterized metabolic changes in proliferating cells upon MYC loss or gain of function. However, metabolic differences betwe...

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Détails bibliographiques
Auteurs principaux: Anso, Elena, Mullen, Andrew R, Felsher, Dean W, Matés, José M, DeBerardinis, Ralph J, Chandel, Navdeep S
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178210/
https://ncbi.nlm.nih.gov/pubmed/24280108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-7
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