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Genetically-defined metabolic reprogramming in cancer
Oncogenes and tumor suppressors regulate cell metabolism. Evidence demonstrates that tumorigenic mutations in these genes tend to orchestrate metabolic activity into a platform that promotes cell survival, growth and proliferation. Recent work has shown that some metabolic enzymes are also mutated i...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466334/ https://ncbi.nlm.nih.gov/pubmed/22858391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2012.06.009 |
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