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Metabolic changes in cancer cells upon suppression of MYC

BACKGROUND: Cancer cells engage in aerobic glycolysis and glutaminolysis to fulfill their biosynthetic and energetic demands in part by activating MYC. Previous reports have characterized metabolic changes in proliferating cells upon MYC loss or gain of function. However, metabolic differences betwe...

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Bibliografski detalji
Glavni autori: Anso, Elena, Mullen, Andrew R, Felsher, Dean W, Matés, José M, DeBerardinis, Ralph J, Chandel, Navdeep S
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178210/
https://ncbi.nlm.nih.gov/pubmed/24280108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-7
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