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Metabolic changes in cancer cells upon suppression of MYC

BACKGROUND: Cancer cells engage in aerobic glycolysis and glutaminolysis to fulfill their biosynthetic and energetic demands in part by activating MYC. Previous reports have characterized metabolic changes in proliferating cells upon MYC loss or gain of function. However, metabolic differences betwe...

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Main Authors: Anso, Elena, Mullen, Andrew R, Felsher, Dean W, Matés, José M, DeBerardinis, Ralph J, Chandel, Navdeep S
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178210/
https://ncbi.nlm.nih.gov/pubmed/24280108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-7
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