Kinomic profiling identifies focal adhesion kinase 1 as a therapeutic target in advanced clear cell renal cell carcinoma

The introduction of targeted therapies has caused a paradigm shift in the treatment of metastatic clear cell (cc)-renal cell carcinoma (RCC). We hypothesized that determining differential kinase activity between primary and metastatic tumor sites may identify critical drivers of progression and rele...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ghosh, Arindam P., Willey, Christopher D., Anderson, Joshua C., Welaya, Karim, Chen, Dongquan, Mehta, Amitkumar, Ghatalia, Pooja, Madan, Ankit, Naik, Gurudatta, Sudarshan, Sunil, Sonpavde, Guru
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438725/
https://ncbi.nlm.nih.gov/pubmed/28418903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16352
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