High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes

Despite the widespread use of kinase-targeted agents in clear cell renal cell carcinoma (CC-RCC), comprehensive kinase activity evaluation (kinomic profiling) of these tumors is lacking. Thus, kinomic profiling of CC-RCC may assist in devising a classification system associated with clinical outcome...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Anderson, Joshua C., Willey, Christopher D., Mehta, Amitkumar, Welaya, Karim, Chen, Dongquan, Duarte, Christine W., Ghatalia, Pooja, Arafat, Waleed, Madan, Ankit, Sudarshan, Sunil, Naik, Gurudatta, Grizzle, William E., Choueiri, Toni K., Sonpavde, Guru
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583516/
https://ncbi.nlm.nih.gov/pubmed/26406598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139267
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