High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes

Despite the widespread use of kinase-targeted agents in clear cell renal cell carcinoma (CC-RCC), comprehensive kinase activity evaluation (kinomic profiling) of these tumors is lacking. Thus, kinomic profiling of CC-RCC may assist in devising a classification system associated with clinical outcome...

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Bibliographic Details
Published in:PLoS One
Main Authors: Anderson, Joshua C., Willey, Christopher D., Mehta, Amitkumar, Welaya, Karim, Chen, Dongquan, Duarte, Christine W., Ghatalia, Pooja, Arafat, Waleed, Madan, Ankit, Sudarshan, Sunil, Naik, Gurudatta, Grizzle, William E., Choueiri, Toni K., Sonpavde, Guru
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583516/
https://ncbi.nlm.nih.gov/pubmed/26406598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139267
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