Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets

Kinases are therapeutically actionable targets. Kinase inhibitors targeting vascular endothelial growth factor receptors (VEGFR) and mammalian target of rapamycin (mTOR) improve outcomes in metastatic clear cell renal cell carcinoma (ccRCC), but are not curative. Metastatic tumor tissue has not been...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ghatalia, Pooja, Yang, Eddy S., Lasseigne, Brittany N., Ramaker, Ryne C., Cooper, Sara J., Chen, Dongquan, Sudarshan, Sunil, Wei, Shi, Guru, Arjun S., Zhao, Amy, Cooper, Tiffiny, Della Manna, Deborah L., Naik, Gurudatta, Myers, Richard M., Sonpavde, Guru
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004806/
https://ncbi.nlm.nih.gov/pubmed/27574806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160924
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