Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets

Kinases are therapeutically actionable targets. Kinase inhibitors targeting vascular endothelial growth factor receptors (VEGFR) and mammalian target of rapamycin (mTOR) improve outcomes in metastatic clear cell renal cell carcinoma (ccRCC), but are not curative. Metastatic tumor tissue has not been...

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Publicado en:PLoS One
Autores principales: Ghatalia, Pooja, Yang, Eddy S., Lasseigne, Brittany N., Ramaker, Ryne C., Cooper, Sara J., Chen, Dongquan, Sudarshan, Sunil, Wei, Shi, Guru, Arjun S., Zhao, Amy, Cooper, Tiffiny, Della Manna, Deborah L., Naik, Gurudatta, Myers, Richard M., Sonpavde, Guru
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004806/
https://ncbi.nlm.nih.gov/pubmed/27574806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160924
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