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PI3K regulation of the SKP-2/p27 axis through mTORC2
The cyclin dependent kinase inhibitor p27 is a key regulator of cell cycle progression. Its expression and localization are altered in several types of malignancies, which has prognostic significance in cancers such as renal cell carcinoma (RCC). S-phase kinase associated protein 2 (SKP-2) is an F-b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707507/ https://ncbi.nlm.nih.gov/pubmed/22733130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.226 |
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