Forkhead followed by disordered tail: The intrinsically disordered regions of FOXO3a

par Wang, Feng, Marshall, Christopher B, Ikura, Mitsuhiko
Publié dans Intrinsically Disord Proteins (2015)

A Non-Canonical Calmodulin Target Motif Comprising a Polybasic Region and Lipidated Terminal Residue Regulates Localization

par Grant, Benjamin M. M., Enomoto, Masahiro, Ikura, Mitsuhiko, Marshall, Christopher B.
Publié dans Int J Mol Sci (2020)

Direct Visualization of Spruce Budworm Antifreeze Protein Interacting with Ice Crystals: Basal Plane Affinity Confers Hyperactivity

par Pertaya, Natalya, Marshall, Christopher B., Celik, Yeliz, Davies, Peter L., Braslavsky, Ido
Publié 2008

Structure-guided Mutation of the Conserved G3-box Glycine in Rheb Generates a Constitutively Activated Regulator of Mammalian Target of Rapamycin (mTOR)

par Mazhab-Jafari, Mohammad T., Marshall, Christopher B., Ho, Jason, Ishiyama, Noboru, Stambolic, Vuk, Ikura, Mitsuhiko
Publié 2014

Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs

par Chandrakumar, Arun A., Coyaud, Étienne, Marshall, Christopher B., Ikura, Mitsuhiko, Raught, Brian, Rottapel, Robert
Publié dans J Cell Biol (2021)

Two Distinct Structures of Membrane-associated Homodimers of GTP- and GDP-bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement

par Lee, Ki-Young, Fang, Zhenhao, Enomoto, Masahiro, Gasmi-Seabrook, Genevieve, Zheng, Le, Koide, Shohei, Ikura, Mitsuhiko, Marshall, Christopher B.
Publié dans Angew Chem Int Ed Engl (2020)

Fluorescence Microscopy Evidence for Quasi-Permanent Attachment of Antifreeze Proteins to Ice Surfaces

par Pertaya, Natalya, Marshall, Christopher B., DiPrinzio, Carlos L., Wilen, Larry, Thomson, Erik S., Wettlaufer, J. S., Davies, Peter L., Braslavsky, Ido
Publié 2007

Multiple Calmodulin-Binding Sites Positively and Negatively Regulate Arabidopsis CYCLIC NUCLEOTIDE-GATED CHANNEL12

par DeFalco, Thomas A., Marshall, Christopher B., Munro, Kim, Kang, Hong-Gu, Moeder, Wolfgang, Ikura, Mitsuhiko, Snedden, Wayne A., Yoshioka, Keiko
Publié dans Plant Cell (2016)

Real-time NMR Study of Three Small GTPases Reveals That Fluorescent 2′(3′)-O-(N-Methylanthraniloyl)-tagged Nucleotides Alter Hydrolysis and Exchange Kinetics

par Mazhab-Jafari, Mohammad T., Marshall, Christopher B., Smith, Matthew, Gasmi-Seabrook, Geneviève M. C., Stambolic, Vuk, Rottapel, Robert, Neel, Benjamin G., Ikura, Mitsuhiko
Publié 2010

Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment

par Wang, Feng, Marshall, Christopher B., Yamamoto, Kazuo, Li, Guang-Yao, Gasmi-Seabrook, Geneviève M. C., Okada, Hitoshi, Mak, Tak W., Ikura, Mitsuhiko
Publié 2012

Point mutations of the mTOR-RHEB pathway in renal cell carcinoma

par Ghosh, Arindam P., Marshall, Christopher B., Coric, Tatjana, Shim, Eun-hee, Kirkman, Richard, Ballestas, Mary E., Ikura, Mitsuhiko, Bjornsti, Mary-Ann, Sudarshan, Sunil
Publié dans Oncotarget (2015)

Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane

par Fang, Zhenhao, Lee, Ki-Young, Huo, Ku-Geng, Gasmi-Seabrook, Geneviève, Zheng, Le, Moghal, Nadeem, Tsao, Ming-Sound, Ikura, Mitsuhiko, Marshall, Christopher B.
Publié dans Proc Natl Acad Sci U S A (2020)

Real-time NMR Study of Guanine Nucleotide Exchange and Activation of RhoA by PDZ-RhoGEF

par Gasmi-Seabrook, Geneviève M. C., Marshall, Christopher B., Cheung, Melissa, Kim, Bryan, Wang, Feng, Jang, Ying Ju, Mak, Tak W., Stambolic, Vuk, Ikura, Mitsuhiko
Publié 2010

p120RasGAP Is a Mediator of Rho Pathway Activation and Tumorigenicity in the DLD1 Colorectal Cancer Cell Line

par Organ, Shawna L., Hai, Josephine, Radulovich, Nikolina, Marshall, Christopher B., Leung, Lisa, Sasazuki, Takehiko, Shirasawa, Senji, Zhu, Chang-Qi, Navab, Roya, Ikura, Mitsuhiko, Tsao, Ming-Sound
Publié 2014

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site

par Mazhab-Jafari, Mohammad T., Marshall, Christopher B., Smith, Matthew J., Gasmi-Seabrook, Geneviève M. C., Stathopulos, Peter B., Inagaki, Fuyuhiko, Kay, Lewis E., Neel, Benjamin G., Ikura, Mitsuhiko
Publié dans Proc Natl Acad Sci U S A (2015)

Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1)

par Fang, Zhenhao, Marshall, Christopher B., Yin, Jiani C., Mazhab-Jafari, Mohammad T., Gasmi-Seabrook, Geneviève M. C., Smith, Matthew J., Nishikawa, Tadateru, Xu, Yang, Neel, Benjamin G., Ikura, Mitsuhiko
Publié dans J Biol Chem (2016)

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

par Azoitei, Mihai L., Noh, Jungsik, Marston, Daniel J., Roudot, Philippe, Marshall, Christopher B., Daugird, Timothy A., Lisanza, Sidney L., Sandí, María-José, Ikura, Mitsu, Sondek, John, Rottapel, Robert, Hahn, Klaus M., Danuser, Gaudenz
Publié dans J Cell Biol (2019)

MARK3-mediated phosphorylation of ARHGEF2 couples the actin and tubulin cytoskeletons to establish cell polarity

par Sandí, María-José, Marshall, Christopher B., Balan, Marc, Coyaud, Étienne, Zhou, Ming, Monson, Daniel M., Ishiyama, Noboru, Chandrakumar, Arun A., La Rose, José, Couzens, Amber L., Gingras, Anne-Claude, Raught, Brian, Xu, Wei, Ikura, Mitsuhiko, Morrison, Deborah K., Rottapel, Robert
Publié dans Sci Signal (2017)

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

par Kano, Yoshihito, Gebregiworgis, Teklab, Marshall, Christopher B., Radulovich, Nikolina, Poon, Betty P. K., St-Germain, Jonathan, Cook, Jonathan D., Valencia-Sama, Ivette, Grant, Benjamin M. M., Herrera, Silvia Gabriela, Miao, Jinmin, Raught, Brian, Irwin, Meredith S., Lee, Jeffrey E., Yeh, Jen Jen, Zhang, Zhong-Yin, Tsao, Ming-Sound, Ikura, Mitsuhiko, Ohh, Michael
Publié dans Nat Commun (2019)