p120RasGAP Is a Mediator of Rho Pathway Activation and Tumorigenicity in the DLD1 Colorectal Cancer Cell Line

KRAS is mutated in ∼40% of colorectal cancer (CRC), and there are limited effective treatments for advanced KRAS mutant CRC. Therefore, it is crucial that downstream mediators of oncogenic KRAS continue to be studied. We identified p190RhoGAP as being phosphorylated in the DLD1 CRC cell line, which...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Organ, Shawna L., Hai, Josephine, Radulovich, Nikolina, Marshall, Christopher B., Leung, Lisa, Sasazuki, Takehiko, Shirasawa, Senji, Zhu, Chang-Qi, Navab, Roya, Ikura, Mitsuhiko, Tsao, Ming-Sound
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897622/
https://ncbi.nlm.nih.gov/pubmed/24465899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086103
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados