<it>BRAF </it>and <it>RAS </it>oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

Por Shirasawa Senji, Sasazuki Takehiko, Andera Ladislav, Koc Michal, Oikonomou Eftychia, Makrodouli Eleni, Pintzas Alexander
Publicado em 2011-09-01

BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

Por Makrodouli, Eleni, Oikonomou, Eftychia, Koc, Michal, Andera, Ladislav, Sasazuki, Takehiko, Shirasawa, Senji, Pintzas, Alexander
Publicado em 2011

Highly Restricted T Cell Repertoire Shaped by a Single Major Histocompatibility Complex–Peptide Ligand in the Presence of a Single Rearranged T Cell Receptor β Chain

Por Fukui, Yoshinori, Hashimoto, Osamu, Inayoshi, Ayumi, Gyotoku, Takahiro, Sano, Tetsuro, Koga, Takahiro, Gushima, Toshifumi, Sasazuki, Takehiko
Publicado em 1998

Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase()()

Por Toda, Kosuke, Kawada, Kenji, Iwamoto, Masayoshi, Inamoto, Susumu, Sasazuki, Takehiko, Shirasawa, Senji, Hasegawa, Suguru, Sakai, Yoshiharu
Publicado no Neoplasia (2016)

Monitoring of S Protein Maturation in the Endoplasmic Reticulum by Calnexin Is Important for the Infectivity of Severe Acute Respiratory Syndrome Coronavirus

Por Fukushi, Masaya, Yoshinaka, Yoshiyuki, Matsuoka, Yusuke, Hatakeyama, Seisuke, Ishizaka, Yukihito, Kirikae, Teruo, Sasazuki, Takehiko, Miyoshi-Akiyama, Tohru
Publicado em 2012

Competition between human cells by entosis

Por Sun, Qiang, Luo, Tianzhi, Ren, Yixin, Florey, Oliver, Shirasawa, Senji, Sasazuki, Takehiko, Robinson, Douglas N, Overholtzer, Michael
Publicado no Cell Res (2014)

Acquisition of Anoikis Resistance Promotes the Emergence of Oncogenic K-ras Mutations in Colorectal Cancer Cells and Stimulates Their Tumorigenicity In Vivo

Por Derouet, Mathieu, Wu, Xue, May, Linda, Hoon Yoo, Byong, Sasazuki, Takehiko, Shirasawa, Senji, Rak, Janusz, Rosen, Kirill V
Publicado em 2007

Oncogenic ras-induced Down-regulation of Pro-apoptotic Protease Caspase-2 Is Required for Malignant Transformation of Intestinal Epithelial Cells

Por Yoo, Byong Hoon, Wang, Yanfei, Erdogan, Mete, Sasazuki, Takehiko, Shirasawa, Senji, Corcos, Laurent, Sabapathy, Kanaga, Rosen, Kirill V.
Publicado em 2011

4E-BP1 Is A Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways That Integrates Their Function in Tumors

Por She, Qing-Bai, Halilovic, Ensar, Ye, Qing, Zhen, Wei, Shirasawa, Senji, Sasazuki, Takehiko, Solit, David B., Rosen, Neal
Publicado em 2010

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells

Por Goulielmaki, Maria, Koustas, Evangelos, Moysidou, Eirini, Vlassi, Margarita, Sasazuki, Takehiko, Shirasawa, Senji, Zografos, George, Oikonomou, Eftychia, Pintzas, Alexander
Publicado no Oncotarget (2016)

HLA-DR2–restricted responses to proteolipid protein 95-116 peptide cause autoimmune encephalitis in transgenic mice

Por Kawamura, Kazuyuki, Yamamura, Takashi, Yokoyama, Kazumasa, Chui, De-Hua, Fukui, Yoshinori, Sasazuki, Takehiko, Inoko, Hidetoshi, David, Chella S., Tabira, Takeshi
Publicado em 2000

Activation of Sterile20-Like Kinase 1 (MST1) in Proteasome Inhibitor Bortezomib-Induced Apoptosis in Oncogenic K-ras-Transformed Cells

Por Teraishi, Fuminori, Guo, Wei, Zhang, Lidong, Dong, Fengqing, Davis, John J., Sasazuki, Takehiko, Shirasawa, Senji, Liu, Jinsong, Fang, Bingliang
Publicado em 2006

Modulation of TNF-α-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-α production and facilitates viral entry

Por Haga, Shiori, Yamamoto, Norio, Nakai-Murakami, Chikako, Osawa, Yoshiaki, Tokunaga, Kenzo, Sata, Tetsutaro, Yamamoto, Naoki, Sasazuki, Takehiko, Ishizaka, Yukihito
Publicado em 2008

Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis; the role of p53 and p21

Por Escandell, José M., Kaler, Pawan, Recio, M. Carmen, Sasazuki, Takehiko, Shirasawa, Senji, Augenlicht, Leonard, Ríos, José-Luis, Klampfer, Lidija
Publicado em 2008

Oncogenic ras-induced Down-regulation of Autophagy Mediator Beclin-1 Is Required for Malignant Transformation of Intestinal Epithelial Cells

Por Yoo, Byong Hoon, Wu, Xue, Li, Yongling, Haniff, Mehnaaz, Sasazuki, Takehiko, Shirasawa, Senji, Eskelinen, Eeva-Liisa, Rosen, Kirill V.
Publicado em 2010

Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis o...

Por Yoo, Byong Hoon, Zagryazhskaya, Anna, Li, Yongling, Koomson, Ananda, Khan, Iman Aftab, Sasazuki, Takehiko, Shirasawa, Senji, Rosen, Kirill V
Publicado no Autophagy (2015)

Impact of oncogenes in tumor angiogenesis: Mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumori...

Por Okada, Futoshi, Rak, Janusz W., Croix, Brad St., Lieubeau, Blandine, Kaya, Mitsunori, Roncari, Luba, Shirasawa, Senji, Sasazuki, Takehiko, Kerbel, Robert S.
Publicado em 1998

Organ-specific autoimmunity in mice whose T cell repertoire is shaped by a single antigenic peptide

Por Oono, Takamasa, Fukui, Yoshinori, Masuko, Sadahiko, Hashimoto, Osamu, Ueno, Takato, Sanui, Terukazu, Inayoshi, Ayumi, Noda, Mayuko, Sata, Michio, Sasazuki, Takehiko
Publicado em 2001

Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage

Por Shirasawa, Senji, Sugiyama, Shigeru, Baba, Iwai, Inokuchi, Junichi, Sekine, Sayaka, Ogino, Keiko, Kawamura, Yuki, Dohi, Taeko, Fujimoto, Manabu, Sasazuki, Takehiko
Publicado em 2004

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

Por Jiang, Hongsi, Pan, Fan, Erickson, Laurie M., Jang, Mei-Shiang, Sanui, Terukazu, Kunisaki, Yuya, Sasazuki, Takehiko, Kobayashi, Masakazu, Fukui, Yoshinori
Publicado em 2005