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Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis; the role of p53 and p21
Cucurbitacins have been shown to inhibit proliferation in a variety of cancer cell lines. The aim of this study was to determine their biological activity in colon cancer cell lines that do not harbor activated STAT3, the key target of cucurbitacin. In order to establish the role of activated kRas i...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519804/ https://ncbi.nlm.nih.gov/pubmed/18561895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.05.004 |
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