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The NF-κB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1β

Progression of colon cancer from microadenoma to macroscopic tumors is coupled to augmentation of canonical Wnt signaling. We recently reported that tumor associated macrophages, through interleukin 1β (IL-1β) dependent phosphorylation of GSK3β, promote Wnt signaling in colon cancer cells, demonstra...

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Detalhes bibliográficos
Main Authors: Kaler, Pawan, Godasi, Bramara N., Augenlicht, Leonard, Klampfer, Lidija
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787930/
https://ncbi.nlm.nih.gov/pubmed/19779850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12307-009-0030-y
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