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Macrophage-derived IL-1β stimulates Wnt signaling and growth of colon cancer cells; a crosstalk interrupted by vitamin D(3)

Tumor associated macrophages mediate the link between inflammation and cancer progression. Here we showed that macrophage-derived soluble factors induce canonical Wnt signaling in colon cancer cells and promote their growth. Tumor cells induced the release of IL-1β from macrophages, which induced ph...

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Main Authors: Kaler, Pawan, Augenlicht, Leonard, Klampfer, Lidija
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783659/
https://ncbi.nlm.nih.gov/pubmed/19701245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.247
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