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Activating Mutations in β-Catenin in Colon Cancer Cells Alter Their Interaction with Macrophages; the Role of Snail

BACKGROUND: Tumor cells become addicted to both activated oncogenes and to proliferative and pro-survival signals provided by the abnormal tumor microenvironment. Although numerous soluble factors have been identified that shape the crosstalk between tumor cells and stroma, it has not been establish...

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Autors principals: Kaler, Pawan, Augenlicht, Leonard, Klampfer, Lidija
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448637/
https://ncbi.nlm.nih.gov/pubmed/23029025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045462
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