DOCK family proteins: key players in immune surveillance mechanisms

Por Kunimura, Kazufumi, Uruno, Takehito, Fukui, Yoshinori
Publicado no Int Immunol (2019)

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo

Por Laurin, Mélanie, Dumouchel, Annie, Fukui, Yoshinori, Côté, Jean-François
Publicado em 2013

DOCK2 Is a Microglial Specific Regulator of Central Nervous System Innate Immunity Found in Normal and Alzheimer’s Disease Brain

Por Cimino, Patrick J., Sokal, Izabela, Leverenz, James, Fukui, Yoshinori, Montine, Thomas J.
Publicado em 2009

DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction

Por Shiraishi, Akira, Uruno, Takehito, Sanematsu, Fumiyuki, Ushijima, Miho, Sakata, Daiji, Hara, Toshiro, Fukui, Yoshinori
Publicado no J Biol Chem (2017)

Dedicator of Cytokinesis 2, A Novel Regulator for Smooth Muscle Phenotypic Modulation and Vascular Remodeling

Por Guo, Xia, Shi, Ning, Cui, Xiao-Bing, Wang, Jia-Ning, Fukui, Yoshinori, Chen, Shi-You
Publicado no Circ Res (2015)

Highly Restricted T Cell Repertoire Shaped by a Single Major Histocompatibility Complex–Peptide Ligand in the Presence of a Single Rearranged T Cell Receptor β Chain

Por Fukui, Yoshinori, Hashimoto, Osamu, Inayoshi, Ayumi, Gyotoku, Takahiro, Sano, Tetsuro, Koga, Takahiro, Gushima, Toshifumi, Sasazuki, Takehiko
Publicado em 1998

DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection

Por Liu, Zhiping, Man, Si Ming, Zhu, Qifan, Vogel, Peter, Frase, Sharon, Fukui, Yoshinori, Kanneganti, Thirumala-Devi
Publicado no Sci Rep (2016)

Cul5-type Ubiquitin Ligase KLHDC1 Contributes to the Elimination of Truncated SELENOS Produced by Failed UGA/Sec Decoding

Por Okumura, Fumihiko, Fujiki, Yuha, Oki, Nodoka, Osaki, Kana, Nishikimi, Akihiko, Fukui, Yoshinori, Nakatsukasa, Kunio, Kamura, Takumi
Publicado no iScience (2020)

Phosphatidic Acid-dependent Recruitment and Function of the Rac Activator DOCK1 during Dorsal Ruffle Formation

Por Sanematsu, Fumiyuki, Nishikimi, Akihiko, Watanabe, Mayuki, Hongu, Tsunaki, Tanaka, Yoshihiko, Kanaho, Yasunori, Côté, Jean-François, Fukui, Yoshinori
Publicado em 2013

Annular PIP(3) accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse

Por Le Floc’h, Audrey, Tanaka, Yoshihiko, Bantilan, Niels S., Voisinne, Guillaume, Altan-Bonnet, Grégoire, Fukui, Yoshinori, Huse, Morgan
Publicado em 2013

Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4(+) T cell–dendritic cell interactions

Por Moalli, Federica, Cupovic, Jovana, Thelen, Flavian, Halbherr, Pascal, Fukui, Yoshinori, Narumiya, Shuh, Ludewig, Burkhard, Stein, Jens V.
Publicado no J Exp Med (2014)

Correction: Annular PIP(3) accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse

Por Le Floc’h, Audrey, Tanaka, Yoshihiko, Bantilan, Niels S., Voisinne, Guillaume, Altan-Bonnet, Grégoire, Fukui, Yoshinori, Huse, Morgan
Publicado no J Exp Med (2017)

Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2

Por Okumura, Fumihiko, Joo-Okumura, Akiko, Obara, Keisuke, Petersen, Alexander, Nishikimi, Akihiko, Fukui, Yoshinori, Nakatsukasa, Kunio, Kamura, Takumi
Publicado no Mol Biol Cell (2017)

Axl Phosphorylates Elmo Scaffold Proteins To Promote Rac Activation and Cell Invasion

Por Abu-Thuraia, Afnan, Gauthier, Rosemarie, Chidiac, Rony, Fukui, Yoshinori, Screaton, Robert A., Gratton, Jean-Philippe, Côté, Jean-François
Publicado no Mol Cell Biol (2014)

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production

Por Ushijima, Miho, Uruno, Takehito, Nishikimi, Akihiko, Sanematsu, Fumiyuki, Kamikaseda, Yasuhisa, Kunimura, Kazufumi, Sakata, Daiji, Okada, Takaharu, Fukui, Yoshinori
Publicado no Front Immunol (2018)

HLA-DR2–restricted responses to proteolipid protein 95-116 peptide cause autoimmune encephalitis in transgenic mice

Por Kawamura, Kazuyuki, Yamamura, Takashi, Yokoyama, Kazumasa, Chui, De-Hua, Fukui, Yoshinori, Sasazuki, Takehiko, Inoko, Hidetoshi, David, Chella S., Tabira, Takeshi
Publicado em 2000

Dimerization of DOCK2 Is Essential for DOCK2-Mediated Rac Activation and Lymphocyte Migration

Por Terasawa, Masao, Uruno, Takehito, Mori, Sayako, Kukimoto-Niino, Mutsuko, Nishikimi, Akihiko, Sanematsu, Fumiyuki, Tanaka, Yoshihiko, Yokoyama, Shigeyuki, Fukui, Yoshinori
Publicado em 2012

Organ-specific autoimmunity in mice whose T cell repertoire is shaped by a single antigenic peptide

Por Oono, Takamasa, Fukui, Yoshinori, Masuko, Sadahiko, Hashimoto, Osamu, Ueno, Takato, Sanui, Terukazu, Inayoshi, Ayumi, Noda, Mayuko, Sata, Michio, Sasazuki, Takehiko
Publicado em 2001

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

Por Jiang, Hongsi, Pan, Fan, Erickson, Laurie M., Jang, Mei-Shiang, Sanui, Terukazu, Kunisaki, Yuya, Sasazuki, Takehiko, Kobayashi, Masakazu, Fukui, Yoshinori
Publicado em 2005

ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation

Por Uematsu, Keiji, Okumura, Fumihiko, Tonogai, Syunsuke, Joo-Okumura, Akiko, Alemayehu, Dawit Hailu, Nishikimi, Akihiko, Fukui, Yoshinori, Nakatsukasa, Kunio, Kamura, Takumi
Publicado no J Cell Biol (2016)