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Phosphatidic Acid-dependent Recruitment and Function of the Rac Activator DOCK1 during Dorsal Ruffle Formation

Activation of receptor tyrosine kinases leads to the formation of two different types of plasma membrane structures: peripheral ruffles and dorsal ruffles. Although the formation of both ruffle types requires activation of the small GTPase Rac, the difference in kinetics suggests that a distinct reg...

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Detalhes bibliográficos
Main Authors: Sanematsu, Fumiyuki, Nishikimi, Akihiko, Watanabe, Mayuki, Hongu, Tsunaki, Tanaka, Yoshihiko, Kanaho, Yasunori, Côté, Jean-François, Fukui, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605628/
https://ncbi.nlm.nih.gov/pubmed/23362269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410423
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