DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

Neutrophils are highly motile leukocytes, and they play important roles in the innate immune response to invading pathogens. Neutrophil chemotaxis requires Rac activation, yet the Rac activators functioning downstream of chemoattractant receptors remain to be determined. We show that DOCK2, which is...

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Detaylı Bibliyografya
Asıl Yazarlar: Kunisaki, Yuya, Nishikimi, Akihiko, Tanaka, Yoshihiko, Takii, Ryosuke, Noda, Mayuko, Inayoshi, Ayumi, Watanabe, Ken-ichi, Sanematsu, Fumiyuki, Sasazuki, Takehiko, Sasaki, Takehiko, Fukui, Yoshinori
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2006
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064308/
https://ncbi.nlm.nih.gov/pubmed/16943182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200602142
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