DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

Neutrophils are highly motile leukocytes, and they play important roles in the innate immune response to invading pathogens. Neutrophil chemotaxis requires Rac activation, yet the Rac activators functioning downstream of chemoattractant receptors remain to be determined. We show that DOCK2, which is...

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Bibliografiske detaljer
Main Authors: Kunisaki, Yuya, Nishikimi, Akihiko, Tanaka, Yoshihiko, Takii, Ryosuke, Noda, Mayuko, Inayoshi, Ayumi, Watanabe, Ken-ichi, Sanematsu, Fumiyuki, Sasazuki, Takehiko, Sasaki, Takehiko, Fukui, Yoshinori
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2006
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064308/
https://ncbi.nlm.nih.gov/pubmed/16943182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200602142
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