Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells

Activating mutations of RAS GTPase contribute to the progression of many cancers, including colorectal carcinoma. So far, attempts to develop treatments of mutant RAS-carrying cancers have been unsuccessful due to insufficient understanding of the salient mechanisms of RAS signaling. We found that R...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Yoo, Byong Hoon, Khan, Iman Aftab, Koomson, Ananda, Gowda, Pramod, Sasazuki, Takehiko, Shirasawa, Senji, Gujar, Shashi, V. Rosen, Kirill
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846558/
https://ncbi.nlm.nih.gov/pubmed/28933585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1370171
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados