BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells

Autophagy is the basic catabolic mechanism that involves cell degradation of unnecessary or dysfunctional cellular components. Autophagy has a controversial role in cancer – both in protecting against tumor progression by isolation of damaged organelles, or by potentially contributing to cancer grow...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Goulielmaki, Maria, Koustas, Evangelos, Moysidou, Eirini, Vlassi, Margarita, Sasazuki, Takehiko, Shirasawa, Senji, Zografos, George, Oikonomou, Eftychia, Pintzas, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891035/
https://ncbi.nlm.nih.gov/pubmed/26802026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6942
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