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BRAF vs RAS oncogenes: are mutations of the same pathway equal? differential signalling and therapeutic implications

As the increased knowledge of tumour heterogeneity and genetic alterations progresses, it exemplifies the need for further personalized medicine in modern cancer management. Here, the similarities but also the differential effects of RAS and BRAF oncogenic signalling are examined and further implica...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Oikonomou, Eftychia, Koustas, Evangelos, Goulielmaki, Maria, Pintzas, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322985/
https://ncbi.nlm.nih.gov/pubmed/25361007
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