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RAS Mutations and Oncogenesis: Not all RAS Mutations are Created Equally

Mutation in RAS proteins is one of the most common genetic alterations observed in human and experimentally induced rodent cancers. In vivo, oncogenic mutations have been shown to occur at exons 12, 13, and 61, resulting in any 1 of 19 possible point mutations in a given tumor for a specific RAS iso...

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Bibliografische gegevens
Hoofdauteurs: Miller, Mark Steven, Miller, Lance D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Research Foundation 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262225/
https://ncbi.nlm.nih.gov/pubmed/22303394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00100
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